Colorectal Cancer Update — NSABP CME Symposium
A Continuing Medical Education Audio Series
STATEMENT OF NEED/TARGET AUDIENCE
Colorectal cancer is among the most common cancers in the United States, and the arena of colorectal cancer treatment continues to evolve. Published results from ongoing clinical trials lead to the emergence of new therapeutic
agents and regimens and changes in indications, doses and schedules for existing treatments. In order to offer optimal patient care — including the option of clinical trial participation — the practicing medical oncologist must be well informed of these advances. To bridge the gap between research and patient care, Colorectal Cancer Update utilizes one-on-one discussions with leading oncology investigators. By providing access to the latest research developments and expert perspectives, this CME activity assists medical oncologists in the formulation of up-to-date clinical management strategies. The purpose of this special issue of Colorectal Cancer Update is to present the most current research developments in targeted and systemic therapies for the treatment of colon and rectal cancers.
GLOBAL LEARNING OBJECTIVES
- Discuss the absolute risks and benefits of adjuvant systemic therapy, including the use of oxaliplatin-containing regimens and the use of capecitabine or intravenous 5-FU in patients with Stage II and Stage III colon cancer.
- Describe the ongoing trials examining the safety and potential efficacy of various biologic therapies in patients with colon cancer.
- Explain the rationale for targeting the EGFR/VEGF pathways and the current and future roles of monoclonal antibodies and oral tyrosine kinase inhibitors in colorectal cancer.
- Describe the current understanding of predictors of response and toxicity and their application to patients with colorectal cancer contemplating anti-VEGF therapy.
- Describe clinical trials of emerging neoadjuvant radiation therapy/chemotherapy approaches to rectal cancer, including the absolute risks and benefits of these regimens.
PURPOSE OF THIS ISSUE OF COLORECTAL CANCER UPDATE
The purpose of this special edition of Colorectal Cancer Update is to support these global objectives by offering the perspectives of Drs Hochster, Hurwitz, O’Connell, Marshall and Wolmark on the integration of emerging clinical research data into the management of colorectal cancer.
ACCREDITATION STATEMENT
Research To Practice is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
CREDIT DESIGNATION STATEMENT
Research To Practice designates this educational activity for a maximum of 5.25 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
HOW TO USE THIS CME ACTIVITY
This CME activity contains both audio and print components. To receive credit, the participant should listen to the CDs or tapes, review the monograph and complete the post-test and evaluation form located in the back of this monograph or on our website. This monograph contains edited comments, clinical trial schemas, graphics and references that supplement the audio program. ColorectalCancerUpdate.com/NSABP_Symposium includes an easy-to-use, interactive version of this monograph with links to relevant full-text articles, abstracts, trial information
and other web resources indicated here in blue underlined text.
