Colorectal Cancer Update
        A Continuing Medical Education Audio Series
      STATEMENT OF NEED/ TARGET AUDIENCE
  Colorectal cancer is among the most common cancers in the United States, and the arena of colorectal cancer
  treatment continues to evolve. Published results from ongoing clinical trials lead to the emergence of new
  therapeutic agents and regimens and changes in indications, doses and schedules for existing treatments.
  In order to offer optimal patient care — including the option of clinical trial participation — the practicing
  medical oncologist must be well informed of these advances. To bridge the gap between research and
  patient care, Colorectal Cancer Update utilizes one-on-one discussions with leading oncology investigators. By
  providing access to the latest research developments and expert perspectives, this CME activity assists medical
oncologists in the formulation of up-to-date clinical management strategies.
GLOBAL LEARNING OBJECTIVES
  -  Critically evaluate the clinical implications of emerging clinical trial data in colorectal cancer treatment, and
    incorporate these data into management strategies in the local and advanced disease settings.
 
  -  Counsel appropriate patients about the availability of ongoing clinical trials.
 
  -  Evaluate the emerging research data on various adjuvant chemotherapy approaches, including the use of
    oxaliplatin-containing regimens and the use of capecitabine or intravenous 5-FU, and explain the absolute
    risks and benefits of these regimens to patients.
 
  -  Evaluate emerging research data on various neoadjuvant radiation therapy/chemotherapy approaches to
    rectal cancer and explain the absolute risks and benefits of these regimens to patients.
 
  -  Integrate emerging data on biologic therapies into management strategies for patients with advanced
    colorectal cancer.
 
PURPOSE OF THIS ISSUE OF COLORECTAL CANCER UPDATE
  The purpose of Issue 3 of Colorectal Cancer Update is to support these global objectives by offering the perspectives
  of Drs Chu, Wolff and Burris on the integration of emerging clinical research data into the management of
  colorectal cancer.
ACCREDITATION STATEMENT
  Research To Practice is accredited by the Accreditation Council for Continuing Medical Education to provide
  continuing medical education for physicians.
CREDIT DESIGNATION STATEMENT
  Research To Practice designates this educational activity for a maximum of 3 AMA PRA Category 1 Credit(s)™.
  Physicians should only claim credit commensurate with the extent of their participation in the activity.
HOW TO USE THIS MONOGRAPH
  This CME activity contains both audio and print components. To receive credit, the participant should listen to the
  CDs or tapes, review the monograph and complete the post-test and evaluation form located in the back of this
  monograph or on our website. This monograph contains edited comments, clinical trial schemas, graphics and
  references that supplement the audio program. ColorectalCancerUpdate.com includes an easy-to-use, interactive
  version of this monograph with links to relevant full-text articles, abstracts, trial information and other web
  resources indicated here in blue underlined text.