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Araki Y et al. Dihydropyrimidine dehydrogenase activity and
thymidylate synthase level are associated with response to 5-fluorouracil
in human colorectal cancer. Kurume Med J 2001;48:93-8. Abstract
Bajetta E et al. Activity and safety of
capecitabine and irinotecan (CPT-11) in association as first line
chemotherapy in advanced colorectal cancer (ACRC). Eur J Cancer
2001;37(Suppl 6):293. Abstract
Becouarn Y et al. Randomized multicenter phase II study comparing
a combination of fluorouracil and folinic acid and alternating irinotecan
and oxaliplatin with oxaliplatin and irinotecan in fluorouracil-pretreated
metastatic colorectal cancer patients. J Clin Oncol 2001;19:4195-201.
Abstract
Falcone A et al. Sequence effect of irinotecan and fluorouracil
treatment on pharmacokinetics and toxicity in chemotherapy-naive
metastatic colorectal cancer patients. J Clin Oncol 2001;19:3456-62.
Abstract
Hoff PM et al. Comparison of oral capecitabine versus intravenous
fluorouracil plus leucovorin as first-line treatment in 605 patients
with metastatic colorectal cancer: Results of a randomized phase
III study. J Clin Oncol 2001;19:2282-92. Abstract
Kerr DJ et al. CPT-11 in combination with capecitabine as first
line chemotherapy for metastatic colorectal cancer (MCRC): Preliminary
results of a phase I/II study. Eur J Cancer 2001;37(Suppl 6):296.
Abstract
Saltz LB et al. Irinotecan plus fluorouracil and leucovorin
for metastatic colorectal cancer. Irinotecan Study Group. N
Engl J Med 2000;343:905-14. Abstract
Scheithauer W et al. Randomized multicenter phase II trial of
oxaliplatin plus irinotecan versus raltitrexed as first-line treatment
in advanced colorectal cancer. J Clin Oncol 2002;20:165-72.
Abstract
Schleucher N et al. Extended phase
I study of capecitabine and weekly irinotecan as first-line chemotherapy
in metastatic colorectal cancer. Eur J Cancer 2001;37(Suppl
6):290. Abstract
Twelves C et al. Capecitabine in combination
with oxaliplatin as first line therapy for patients (pts) with advanced
or metastatic colorectal cancer (ACRC): Preliminary results of an
international multicenter phase II study. Eur J Cancer 2001;37(Suppl
6):272. Abstract
Van Cutsem E et al. Oral capecitabine compared with intravenous
fluorouracil plus leucovorin in patients with metastatic colorectal
cancer: Results of a large phase III study. J Clin Oncol 2001;19:4097-106.
Abstract
Zeuli M et al. Oxaliplatin and capecitabine
in advanced colorectal cancer: A pilot study. Eur J Cancer 2001;37(Suppl
6):309. Abstract
Pharmaceutical agents discussed in this program
capecitabine |
Xeloda® |
Roche Laboratories, Inc. |
leucovorin |
Wellcovorin® |
GlaxoSmithKline |
irinotecan (CPT-11) |
Camptosar® |
Pharmacia Corporation |
oxaliplatin |
Eloxatin® |
Sanofi-Synthelabo, Inc |
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